Melatonin - contraindications to use
From this article you will learn who should be cautious with melatonin supplementation.
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.Melatonin is a neurohormone naturally secreted by our body. We sometimes make up for its deficiency with supplementation. Unfortunately, not everyone can take synthetic melatonin.
.Ahead of a long-haul flight and not sure how to adapt to the new time zone? Or perhaps a loved one is struggling with a sleep disorder? Melatonin supplementation seems like a good idea, due to its proven properties. However, before you sip the tablet, check what contraindications to use are indicated by Dr Witold Tomaszewski, M.D.
.Description of contents:
.- Melatonin - what is it? .
- Melatonin contraindications to use .
- Summary .
Sleep Well - dietary supplement for good sleep and tranquillity
.Sleep Well is a calming and relaxing dietary supplement with a standardised complex of CALMOMIX® herbal extracts and high quality magnesium.
See also:
.- Melatonin: action, contraindications, indications for use
- Melatonin for sleep - properties and dosage .
- Melatonin - dosage
- Sleep hygiene - 8 proven ways to get a good night's sleep
Melatonin - what is it?
.Melatonin -called the sleep hormone-regulates our circadian rhythm, while exhibiting a number of other health-promoting properties. Among other things, it modulates the immune system response and is a very effective antioxidant. It is secreted mainly by a small gland in our brain - the pineal gland. Its abnormal levels can be regulated through healthy supplementationand.
Melatonin - contraindications to use
.Although melatonin is a hormone naturally produced by the body, not everyone can supplement it.
Contraindications to melatonin use includeand:
.- Hypersensitivity to melatonin. The use of melatonin in cases of hypersensitivity exposes one to unpleasant symptoms such as nausea or vomiting. .
- Pregnancy and breastfeeding. There is insufficient evidence for the safety of melatonin use during pregnancy or breastfeeding.
- Rheumatoid arthritis (RA). Some studies suggest that melatonin increases pro-inflammatory activity and thus promotes disease activity in RA, hence caution is advised.
- Kidney diseases. In patients on dialysis, there is a risk of increased side effects due to the inability to adequately purify melatonin.
- Hepatic diseases. In patients with impaired liver function, caution should be exercised due to the reduced ability to metabolise melatonin.
- Cinical alcoholic disease. Taking melatonin with alcohol is dangerous to our health. Alcohol reduces or intensifies the effects of melatonin and can cause drowsiness, difficulty breathing, dizziness. .
- Simultaneous use with drugs that interact interact with melatonin. These include steroid drugs, anticoagulants, drugs used to treat diabetes, some antidepressants and benzodiazepines. Caution should be exercised when using hormonal contraception. .
Pharmovit Melatonin with melissa
- Active ingredients: melatonin, lemon balm leaf extract
- Form: capsules .
- Packaging: 60 capsules .
- Dose: 1 capsule per day .
- Sufficient for: 60 days .
Product description
Melatonin enriched with the relaxing and calming effects of lemon balm. Supplementation will help you to shortenóy your sleep time and reduce the number of night wakings. Your sleep will be deep and restorative, and you will get up in the morning feeling refreshed and rested.
Melatonin, unlike other sleep aids, does not interfere with daytime functioning. Your concentration will not suffer, in fact it will improve, thanks to the right dose of healthy sleep.
Melatonin is the best way to improve your concentration.
Pros and cons
Melatonin enriched with the relaxing and calming effects of lemon balm. Supplementation will help you to shortenóy your sleep time and reduce the number of night wakings. Your sleep will be deep and restorative, and you will get up in the morning feeling refreshed and rested.
Melatonin, unlike other sleep aids, does not interfere with daytime functioning. Your concentration will not suffer, in fact it will improve, thanks to the right dose of healthy sleep.
Melatonin is the best way to improve your concentration.
Additional information
Melatonin enriched with the relaxing and calming effects of lemon balm. Supplementation will help you to shortenóy your sleep time and reduce the number of night wakings. Your sleep will be deep and restorative, and you will get up in the morning feeling refreshed and rested.
Melatonin, unlike other sleep aids, does not interfere with daytime functioning. Your concentration will not suffer, in fact it will improve, thanks to the right dose of healthy sleep.
Melatonin is the best way to improve your concentration.
User review
Melatonin enriched with the relaxing and calming effects of lemon balm. Supplementation will help you to shortenóy your sleep time and reduce the number of night wakings. Your sleep will be deep and restorative, and you will get up in the morning feeling refreshed and rested.
Melatonin, unlike other sleep aids, does not interfere with daytime functioning. Your concentration will not suffer, in fact it will improve, thanks to the right dose of healthy sleep.
Melatonin is the best way to improve your concentration.
Aura Herbals Melatonin Control + Melissa
- Active ingredients: melatonin, lemon balm extract
- Form: aerosol .
- Dose: 1 or 2 applications .
Product description
A supplement to replenish melatonin deficiencies in the body with an interesting aerosol form. The combination of melatonin with gently calming melissa speeds up falling asleep and ensures a restful night's sleep.
Advised for people suffering from sleep problems, working night shifts and frequently changing time zones.
Pros and cons
A supplement to replenish melatonin deficiencies in the body with an interesting aerosol form. The combination of melatonin with gently calming melissa speeds up falling asleep and ensures a restful night's sleep.
Advised for people suffering from sleep problems, working night shifts and frequently changing time zones.
Additional information
A supplement to replenish melatonin deficiencies in the body with an interesting aerosol form. The combination of melatonin with gently calming melissa speeds up falling asleep and ensures a restful night's sleep.
Advised for people suffering from sleep problems, working night shifts and frequently changing time zones.
Saffron with melatonin Yango
- Active ingredients: melatonin, saffron stigma – extract
- Form: capsules .
- Dose: 1 capsule daily .
- Sufficient for: 60 days .
Product description
Saffron with melatonin by Yango supports the quality of sleep and alleviates sleep problems. The saffron contained in it counteracts depressive states, alleviates anxiety and stress, thus improving relaxation, emotional balance and a good mood.
Melatonin, in turn, helps to regulate the sleep-wake cycle, which promotes faster sleep and easier adaptation to time zone changes. The use of this supplement also supports the body's natural regeneration processes during sleep.
Melatonin also helps to regulate the sleep-wake cycle.
Pros and cons
Saffron with melatonin by Yango supports the quality of sleep and alleviates sleep problems. The saffron contained in it counteracts depressive states, alleviates anxiety and stress, thus improving relaxation, emotional balance and a good mood.
Melatonin, in turn, helps to regulate the sleep-wake cycle, which promotes faster sleep and easier adaptation to time zone changes. The use of this supplement also supports the body's natural regeneration processes during sleep.
Melatonin also helps to regulate the sleep-wake cycle.
Additional information
Saffron with melatonin by Yango supports the quality of sleep and alleviates sleep problems. The saffron contained in it counteracts depressive states, alleviates anxiety and stress, thus improving relaxation, emotional balance and a good mood.
Melatonin, in turn, helps to regulate the sleep-wake cycle, which promotes faster sleep and easier adaptation to time zone changes. The use of this supplement also supports the body's natural regeneration processes during sleep.
Melatonin also helps to regulate the sleep-wake cycle.
NOW FOODS Melatonin 1 mg
- Active ingredients: melatonin, magnesium, niacin, vitamin B6
- Form: tablets .
- Dose: 2 tablets before bed .
- Sufficient for: over 3 months .
Product description
Melatonin is the so-called sleep hormone thatós involved in regulating your diurnal rhythm. It makes you feel sleepy in the evening. Magnesium, vitamin B6 and niacin support the nervous system and can also help to improve the quality and length of sleep.
Pros and cons
Melatonin is the so-called sleep hormone thatós involved in regulating your diurnal rhythm. It makes you feel sleepy in the evening. Magnesium, vitamin B6 and niacin support the nervous system and can also help to improve the quality and length of sleep.
Additional information
Melatonin is the so-called sleep hormone thatós involved in regulating your diurnal rhythm. It makes you feel sleepy in the evening. Magnesium, vitamin B6 and niacin support the nervous system and can also help to improve the quality and length of sleep.
User review
Melatonin is the so-called sleep hormone thatós involved in regulating your diurnal rhythm. It makes you feel sleepy in the evening. Magnesium, vitamin B6 and niacin support the nervous system and can also help to improve the quality and length of sleep.
Dr Jacob's Melatonin + B12
- Active ingredients: melatonin, vitamin B12
- Form: sucking pastilles .
- Dosage: 1 lozenge per day .
- Sufficient for: 60 days .
Product description
Sweet pleasures in the evening are rather forbidden. Well, unless it's cherry lozenges with melatonin and vitamin B12, whichóre going to improve the quality of your sleep.
One tablet in the evening will shorten your sleep time and stop you waking up.
One tablet in the evening will shortenóyour time to fall asleep and stop you waking up during the night. The addition of vitamin B12 will improve the functioning of the nervous system, making you even better rested.
The following tablets will help to improve the quality of your sleep.
Pros and cons
Sweet pleasures in the evening are rather forbidden. Well, unless it's cherry lozenges with melatonin and vitamin B12, whichóre going to improve the quality of your sleep.
One tablet in the evening will shorten your sleep time and stop you waking up.
One tablet in the evening will shortenóyour time to fall asleep and stop you waking up during the night. The addition of vitamin B12 will improve the functioning of the nervous system, making you even better rested.
The following tablets will help to improve the quality of your sleep.
Additional information
Sweet pleasures in the evening are rather forbidden. Well, unless it's cherry lozenges with melatonin and vitamin B12, whichóre going to improve the quality of your sleep.
One tablet in the evening will shorten your sleep time and stop you waking up.
One tablet in the evening will shortenóyour time to fall asleep and stop you waking up during the night. The addition of vitamin B12 will improve the functioning of the nervous system, making you even better rested.
The following tablets will help to improve the quality of your sleep.
User review
Sweet pleasures in the evening are rather forbidden. Well, unless it's cherry lozenges with melatonin and vitamin B12, whichóre going to improve the quality of your sleep.
One tablet in the evening will shorten your sleep time and stop you waking up.
One tablet in the evening will shortenóyour time to fall asleep and stop you waking up during the night. The addition of vitamin B12 will improve the functioning of the nervous system, making you even better rested.
The following tablets will help to improve the quality of your sleep.
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Good Night Yango
- Active ingredients: melatonin, valerian, verbena, hops cone, L-tryptophan, passionflower
- Form: capsules .
- Dose: 1 capsule daily .
- Sufficient for: 50 days .
Product description
Good Night is a natural dietary supplement thatós designed to support healthy and relaxing sleep. It is helpful for peopleób struggling with sleep problems, as it uses the unique properties of plant extractsób, affecting the efficiency and length of sleep.
With this supplement, youóll enjoy greater energy, improved mood and concentration. Adequate and effective sleep also contributes to better performance
in sports and studies and affects our immunity.
Good Night contains active plant ingredients such as melatonin and extracts of valerian, hops cones, verbena and passionflower.
.Pros and cons
Good Night is a natural dietary supplement thatós designed to support healthy and relaxing sleep. It is helpful for peopleób struggling with sleep problems, as it uses the unique properties of plant extractsób, affecting the efficiency and length of sleep.
With this supplement, youóll enjoy greater energy, improved mood and concentration. Adequate and effective sleep also contributes to better performance
in sports and studies and affects our immunity.
Good Night contains active plant ingredients such as melatonin and extracts of valerian, hops cones, verbena and passionflower.
.Additional information
Good Night is a natural dietary supplement thatós designed to support healthy and relaxing sleep. It is helpful for peopleób struggling with sleep problems, as it uses the unique properties of plant extractsób, affecting the efficiency and length of sleep.
With this supplement, youóll enjoy greater energy, improved mood and concentration. Adequate and effective sleep also contributes to better performance
in sports and studies and affects our immunity.
Good Night contains active plant ingredients such as melatonin and extracts of valerian, hops cones, verbena and passionflower.
.Sleep Well Yango
- Active ingredients: melatonin, L-tryptophan, valerian, passionflower, hops cone, L-theanine, vitamin B6, vitamin B12.
- Form: capsules .
- Dose: 1 capsule per day .
- Sufficient for: 90 days .
Product description
YANGO Sleep Well is a dietary supplement dedicated to peopleób wishing to optimise sleep and improve its quality. The active ingredients are substances that support the process of falling asleep and the nervous system. Melatonin and L-tryptophan accelerate falling asleep by supporting natural processes.
.Gosol and hop cone help to relax, while vitamins B6 and B12 support the nervous system.
Pros and cons
YANGO Sleep Well is a dietary supplement dedicated to peopleób wishing to optimise sleep and improve its quality. The active ingredients are substances that support the process of falling asleep and the nervous system. Melatonin and L-tryptophan accelerate falling asleep by supporting natural processes.
.Gosol and hop cone help to relax, while vitamins B6 and B12 support the nervous system.
Additional information
YANGO Sleep Well is a dietary supplement dedicated to peopleób wishing to optimise sleep and improve its quality. The active ingredients are substances that support the process of falling asleep and the nervous system. Melatonin and L-tryptophan accelerate falling asleep by supporting natural processes.
.Gosol and hop cone help to relax, while vitamins B6 and B12 support the nervous system.
ALLDEYNN SLEEPROSE
- Active ingredients: melatonin, amino acids, L-glutamine, GABA, L-tryptophan, ashwagandha, L-theanine, magnesium, saffron extract, zinc, vitamin B6
- Form: powder .
- Packaging: 280 g
- Serving: 14 g
- Sufficient for: 20 days .
Product description
A careful composition of as many as 11 active ingredients which calm you down, improve the quality of sleep and support post-workout regeneration. Recommended for people who want to improve their sleep and relax.
>.Pros and cons
A careful composition of as many as 11 active ingredients which calm you down, improve the quality of sleep and support post-workout regeneration. Recommended for people who want to improve their sleep and relax.
>.Additional information
A careful composition of as many as 11 active ingredients which calm you down, improve the quality of sleep and support post-workout regeneration. Recommended for people who want to improve their sleep and relax.
>.User review
A careful composition of as many as 11 active ingredients which calm you down, improve the quality of sleep and support post-workout regeneration. Recommended for people who want to improve their sleep and relax.
>.
Product description
Tablets to facilitate falling asleep and help maintain uninterrupted sleep. The formula is based on natural ingredients such as melatonin, minerals and plant extracts.
By taking Good Sleep about an hour before you go to bed, you can improve the quality of your sleep and negate feelings of fatigue during the day. Healthy sleep will support your concentration and give you energy.
Pros and cons
Tablets to facilitate falling asleep and help maintain uninterrupted sleep. The formula is based on natural ingredients such as melatonin, minerals and plant extracts.
By taking Good Sleep about an hour before you go to bed, you can improve the quality of your sleep and negate feelings of fatigue during the day. Healthy sleep will support your concentration and give you energy.
Additional information
Tablets to facilitate falling asleep and help maintain uninterrupted sleep. The formula is based on natural ingredients such as melatonin, minerals and plant extracts.
By taking Good Sleep about an hour before you go to bed, you can improve the quality of your sleep and negate feelings of fatigue during the day. Healthy sleep will support your concentration and give you energy.
SFD SLEEP PRO 90 capsules, a supplement for a good night's sleep
- Active ingredients: extract of oatmeal, lemon balm, common hops, saffron, vitamin B6, magnesium, zinc, L-theanine, L-tryptophan, GABA, soy lecithin .
- Form: capsules .
- Dose: 2 capsules before bed .
- Sufficient for: 45 days .
Product description
Product contains a range of specially selected ingredientsóthat support calmness and sleep quality. Recommended for stressful periods or moderate sleep problems.
Pros and cons
Product contains a range of specially selected ingredientsóthat support calmness and sleep quality. Recommended for stressful periods or moderate sleep problems.
Additional information
Product contains a range of specially selected ingredientsóthat support calmness and sleep quality. Recommended for stressful periods or moderate sleep problems.
User review
Product contains a range of specially selected ingredientsóthat support calmness and sleep quality. Recommended for stressful periods or moderate sleep problems.
Sleep Well - dietary supplement for good sleep and tranquillity
.Sleep Well is a calming and relaxing dietary supplement with the standardised CALMOMIX® complex of herbal extracts and high quality magnesium.
See also:
.- Sleep hygiene - 8 proven ways to get a good night's sleep
- Best over-the-counter sleep pills
- Best sedation pills without a prescription
- How to take care of your mental health during a period of depressed mood
- Ashwagandha - properties, contraindications, effects on sleep
- Indian ginseng - properties, contraindications, opinions
- Adaptogens - what they are, types, effects, supplementation .
- Passionflower (passiflora incarnata) - effects on sleep and other properties
Summary
.Synthetic melatonin can support us with moderate sleep problems, regulate the diurnal cycle or help us adapt to a new time zone. However, it is important to pay attention to the contraindications in order to avoid side effects.
Do you pay attention to contraindications and interactions when taking a supplement? Let me know in the comments. I, for one, have recently been studying the leaflets before I take something - you can be surprised when reading!
FAQ
.Who can't take melatonin?
.Contraindications to the use of melatonin include: hypersensitivity to melatonin, pregnancy and breastfeeding, kidney and liver disease, active alcoholism, use of medications that interact with melatonin, e.g. steroids, anticoagulants, antidepressants and benzodiazepines.
Does melatonin harm the heart?
.No, melatonin does not harm the heart. Research suggests that melatonin has valuable effects on cardiovascular health, blood pressure and endothelial function and may be beneficial for people with heart failure. If you are being treated for heart disease, consult your doctor before supplementation.
Is melatonin safe?
.Yes, many studies have confirmed that melatonin is safe to use. It does not cause addiction and when taken correctly, it does not cause side effects. Remember, it is important to take it sensibly dosing and to use it regularly to feel the positive effects.
Does melatonin cure insomnia?
.No, melatonin does not cure insomnia. Insomnia is a serious, complex disorder that requires medical care and the conscious implementation of sleep hygiene into your daily routine. Melatonin will help you with moderate sleep problems, but prolonged discomfort should be consulted with a doctor.
Do herbs for sleep help?
.Yes, many substances of plant origin can aid sleep. The unique safety profile of herbal products and their wide tolerance by patients make a strong case for their support for moderate sleep problems.
Does melatonin work straight away?
.No, melatonin does not work immediately. Melatonin given orally starts to take effect after about 30 min. You should consume it about 60 minutes before bedtime. Remember that you will achieve the best results through safe dosing and systematic use.
Is melatonin a sleep medication?
.No, melatonin is not a sleep medication. Melatonin in supplements or medicines is a synthetic hormone. sleep medications are special pharmacological preparations designed to treat sleep disorders. They are prescribed by prescription and need to be taken under close medical supervision.
Can children take melatonin?
.There are studies that suggest that melatonin supplementation is beneficial for children aged 3 to 15 years if they present with: sleep disorders, neurodevelopmental disorders, difficulty falling asleep, frequent awakenings during the night, shortened sleep duration, atopic dermatitis. Treatment must be carried out under close medical supervision.
Do you get fat from melatonin?
.No, you do not get fat from melatonin supplementation. It is the quality of sleep that can affect weight gain - sleep disturbances affect hormones, including hunger and satiety hormones (ghrelin, leptin). Not getting enough sleep can lead to an increased appetite, resulting in a calorie surplus and weight gain.
Can melatonin be overdosed?
.Melatonin overdose is difficult to define, as there is no official safe dose for everyone. Individual responses to an overdose of melatonin can vary considerably due to various factors, such as age, gender and time of administration.
Is melatonin addictive?
.No, melatonin is not addictive. There is no scientific evidence that melatonin users develop a tolerance to the supplement. Melatonin has no addictive potential, unlike sleep medications.
Melatonin is not helping me. What should I do?
.If you have been supplementing with melatonin regularly for 2 weeks, have implemented the principles of sleep hygiene and are taking care of a healthy diet, but are still experiencing sleep-related disorders, see your doctor. This could be a symptom of an illness and your body is signalling in this way that you need to seek specialist help.
What should I do if I have insomnia?
.Insomnia is a serious disorder that requires comprehensive treatment. The best results come from implementing the principles of sleep hygiene, consulting a doctor and sessions with a psychologist or psychotherapist. Insomnia can be effectively cured.
.What is the lethal dose of melatonin?
.To date, no case of death after melatonin ingestion has been described in scientific studies. The lethal dose in humans is not known. It is important not to consume large amounts of melatonin, as excess can cause unpleasant side effects.
What should melatonin not be combined with?
.Melatonin must not be combined with: alcohol, oestrogens (e.g. in oral hormonal contraception), glucocorticosteroids, benzodiazepines, and sedative drugs, antidepressants, anticoagulants, anti-inflammatory drugs, antiepileptic drugs.
After what time does melatonin start to take effect?
.Melatonin in tablets begins to take effect approximately 30 minutes after ingestion, and melatonin in drop, spray or leaf form approximately 15 minutes after ingestion. The best sleep-supporting effects are observed gradually, usually after 2 weeks of regular consumption.
Does melatonin help with sleep?
.Yes, according to scientific studies melatonin helps sleep. Its action helps you fall asleep, improves the quality and length of sleep and reduces the number of awakenings during the night. The use of melatonin can be an effective support for the treatment of moderate sleep problems.
What is the best melatonin?
.The best melatonin is Sleep Well a dietary supplement with melatonin 1 mg and the standardised herbal extract complex CALMOMIX. The composition comprehensively cares for calming the body and prepares the body and mind for sleep. Sleep Well from Natu.Care has very good reviews among users.
Sources
.See all
.Grivas, T. B., & Savvidou, O. D. (2007). Melatonin the "light of night" in human biology and adolescent idiopathic scoliosis. Scoliosis, 2(1), 6. https://doi.org/10.1186/1748-7161-2-6
Fatemeh, G., Sajjad, M., Niloufar, R., Neda, S., Leila, S., & Khadijeh, M. (2022). Effect of melatonin supplementation on sleep quality: A systematic review and meta-analysis of randomized controlled trials. Journal of Neurology, 269(1), 205-216. https://doi.org/10.1007/s00415-020-10381-w
Melatonin Dosage by Age and Weight. (2021, May 28). Sleep Foundation. https://www.sleepfoundation.org/melatonin/melatonin-dosage-how-much-should-you-take
Melatonin: What You Need To Know. (n.d.). NCCIH. Retrieved 17 March 2023, from https://www.nccih.nih.gov/health/melatonin-what-you-need-to-know
Savage, R. A., Zafar, N., Yohannan, S., & Miller, J.-M. M. (2022). Melatonin. In StatPearls. StatPearls Publishing. http://www.ncbi.nlm.nih.gov/books/NBK534823/
.Vural, E. M. S., van Munster, B. C., & de Rooij, S. E. (2014). Optimal Dosages for Melatonin Supplementation Therapy in Older Adults: A Systematic Review of Current Literature. Drugs & Aging, 31(6), 441-451. https://doi.org/10.1007/s40266-014-0178-0
Editorials
Meet the teamNatu.Care Editor
Nina Wawryszuk specialises in sports supplementation, strength training and psychosomatics. On a daily basis, in addition to writing articles for Natu.Care, as a personal trainer she helps athletes improve their performance through training, diet and supplementation.
Doctor of Medicine
Doctor of Medicine, food and pharmaceutical law expert and experienced medical professional.
Editor
Graduate of Journalism and Artes Liberales at the University of Warsaw. Since 2017, he has been working with the biggest portals in Poland and abroad as an editor. Previously worked for 3 years in one of the leading pharmaceutical companies - he knows the health and beauty industry inside out. In his free time, he most enjoys playing tennis or skiing.
Fact-checker
Agata Jach is in charge of verifying quoted sources and checking that published content is truthful.
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Melatonin is a neurohormone naturally secreted by the body that regulates our day and night cycle.
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