Vitamin B1 (thiamine) - properties, sources, deficiency, excess

Vitamin B1 called thiamine is responsible for the nervous, immune and cardiovascular systems.

Ludwik Jelonek - AuthorAuthorLudwik Jelonek
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Ludwik Jelonek
Natu.Care Editor

Ludwik Jelonek is the author of more than 2,500 texts published on leading portals. His content has found its way into services such as Ostrovit and Kobieta Onet. At Natu.Care, Ludwik educates people in the most important area of life - health.

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Julia Skrajda - Reviewed by
Reviewed by
Julia Skrajda
Clinical nutritionist

A clinical nutritionist, she works in the profession and creates personalised menus and recommendations for disease entities.

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Michael Tomaszewski - Edited byEdited byMichael Tomaszewski
Michael Tomaszewski - Edited by
Edited by
Michael Tomaszewski
Editor

Graduate of Journalism and Artes Liberales at the University of Warsaw. Since 2017, he has been working with the biggest portals in Poland and abroad as an editor. Previously worked for 3 years in one of the leading pharmaceutical companies - he knows the health and beauty industry inside out. In his free time, he most enjoys playing tennis or skiing.

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Emilia Moskal specialises in medical and psychological texts, including content for medical entities. She is a fan of simple language and reader-friendly communication. At Natu.Care, she writes educational articles.

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Vitamin B1 (thiamine) - properties, sources, deficiency, excess
Updated:
13 min
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First. Mysterious. Forgotten. That's exactly what vitamin B1 is. Most people don't know much about it, so together with nutritionist Karolina Król-Lach, I've put together a solid dose of thiamine knowledge for you. What is it? What are its properties? What are the symptoms of thiamine deficiency and excess? You will find the answers to these and other questions in this article!

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Description of contents:

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  1. What is vitamin B1?
  2. .
  3. Properties of thiamine
  4. .
  5. Thiamine requirements
  6. .
  7. Sources of thiamine
  8. .
  9. Vitamin B1 deficiency
  10. .
  11. Vitamin B1 excess
  12. .
  13. Thiamine supplementation
  14. .
  15. Vitamin B1 during pregnancy
  16. .
  17. Tiamine and alcohol
  18. .
  19. Interactions of vitamin B1 with drugs
  20. .
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See also:

What is vitamin B1?

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Vitamin B1 (thiamine) is a vitamin water-soluble. It is responsible for the functioning of cells in the body, as well as the production of energy from nutrients. The body only stores trace amounts of thiamine in the liver. It is therefore necessary to take vitamin B1 daily with the dietand.

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Vitamin B1 was discovered and isolated from rice bran by a Polish biochemist - Kazimierz Funk. Thiamine is a water-soluble vitamin that plays a key role in tissue respiration. The body also uses it in numerous metabolic processes, for example during the conversion of food into energy
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Carolina Król-LachDietitian

Properties of thiamine 

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Vitamin B1 is an essential nutrient that affects numerous processes in the body. How does thiamine work?

  • Increases energy production. The primary role of carbohydrates is to provide the body with energy. Vitamin B1 plays a very important role in this process. It helps the body's cells convert carbohydrates into energyand.
  • .
  • Helps fight depression. Vitamin B1 relieves symptoms of depression and improves mood. Furthermore, thiamine deficiency has been linked to poor moodand.
  • .
  • Helps people with diabetes. Research suggests that taking thiamine has a positive effect on blood sugar levels. It doesn't stop there, vitamin B1 lowers high blood pressure and prevents cardiac complications in people with diabetesand.
  • Reduces symptoms of sepsis. Tiamine in combination withvitamin C alleviates symptoms of sepsis. It may also reduce the risk of kidney failure, which often follows infectionand.
  • Prevents nerve damage. B vitamins, including thiamine, positively influence regeneration of damaged nerves. Its deficiency leads to peripheral neuropathy. Furthermore, combining vitamin B1 with vitamin B12 may alleviate nerve pain in people with diabetesand.
  • Improves memory.  Thiamine supplementation may improve memory and concentrationand.
  • .
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Vitamin B1 is thought to regulate thyroid function. In cases of hyperthyroidism of this organ, increased excretion of vitamin B1 is observed with urine
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Julia Skrajda.

Julia SkrajdaDietitian

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How else does thiamine workand?

    .
  • Alleviates symptoms of premenstrual syndrome.
  • .
  • Maintains the health of the nervous system.
  • Influences immunity.
  • Contributes to the maintenance of normal energy metabolism.
  • Prevents cardiovascular disease.
  • .
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Thiamine has an impact on the functioning of the nervous system and heart function. It doesn't stop there, it is involved in the flow of electrolytes to nerve and muscle cells
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Carolina Król-LachDietitian

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Vitamin C also boosts immunity and affects heart function. Read more about it: Vitamin C - what it is, properties, effects, deficiency.

For sucking

Dr Jacob's Melatonin + B12

4.8
Dr Jacob's Melatonin + B12
  • Active ingredients: melatoninvitamin B12
  • Form: sucking pastilles
  • .
  • Dosage: 1 lozenge per day
  • .
  • Sufficient for: 60 days
  • .
Product description

Sweet pleasures in the evening are rather forbidden. Well, unless it's cherry lozenges with melatonin and vitamin B12, whichóre going to improve the quality of your sleep.

One tablet in the evening will shorten your sleep time and stop you waking up.

One tablet in the evening will shortenóyour time to fall asleep and stop you waking up during the night. The addition of vitamin B12 will improve the functioning of the nervous system, making you even better rested.

The following tablets will help to improve the quality of your sleep.

Pros and cons

Sweet pleasures in the evening are rather forbidden. Well, unless it's cherry lozenges with melatonin and vitamin B12, whichóre going to improve the quality of your sleep.

One tablet in the evening will shorten your sleep time and stop you waking up.

One tablet in the evening will shortenóyour time to fall asleep and stop you waking up during the night. The addition of vitamin B12 will improve the functioning of the nervous system, making you even better rested.

The following tablets will help to improve the quality of your sleep.

Additional information

Sweet pleasures in the evening are rather forbidden. Well, unless it's cherry lozenges with melatonin and vitamin B12, whichóre going to improve the quality of your sleep.

One tablet in the evening will shorten your sleep time and stop you waking up.

One tablet in the evening will shortenóyour time to fall asleep and stop you waking up during the night. The addition of vitamin B12 will improve the functioning of the nervous system, making you even better rested.

The following tablets will help to improve the quality of your sleep.

User review

Sweet pleasures in the evening are rather forbidden. Well, unless it's cherry lozenges with melatonin and vitamin B12, whichóre going to improve the quality of your sleep.

One tablet in the evening will shorten your sleep time and stop you waking up.

One tablet in the evening will shortenóyour time to fall asleep and stop you waking up during the night. The addition of vitamin B12 will improve the functioning of the nervous system, making you even better rested.

The following tablets will help to improve the quality of your sleep.

Natu.Care editor's choiceOur product

Natu.Care B-complex Formula

5.0
Natu.Care B-complex Formula
  • Active ingredients (in the recommended portion):

    • vitamin B1 (thiamine)

    • vitamin B2 (riboflavin)
    • vitamin B3 (niacin)

    • vitamin B5 (pantothenic acid)

    • vitamin B6

    • biotin (vitamin B7)

    • folic acid (vitamin B9)

    • vitamin B12

  • Who is it for and what for?

    The product is intended for adults who wish to supplement their diet with B vitamins in one cohesive formula, rather than reaching for individual preparations.

  • Form:

    Capsules allow for convenient and precise use of the product as part of daily supplementation.

  • Daily portion:

    The recommended daily portion is 1 capsule, taken according to the manufacturer's instructions on the packaging.

  • Lasts for:

    The product lasts for 60 days of use, according to the information provided by the manufacturer.

 

 

Check Price
Over 100,000 happy customers
Product Description

B-Complex Formula is a dietary supplement containing a complete set of B vitamins, designed for the daily supplementation of adults' diets. The product has been developed as an organised form of supplementation, without combining ingredients with stimulating additives. It serves as a consistent element of daily nutritional routine.

Pros and Cons

Pros:

  • complete set of B vitamins in one preparation

  • simple, clear formula

  • convenient capsule form

Cons:

  • product intended solely for adults

  • pregnant women should consult usage before use

  • requires regular use

 

Ideal for vegans

SOLGAR natural vitamin B12

5.0
SOLGAR natural vitamin B12
  • Active ingredients: vitamin B12
  • Form: tablets 
  • .
  • Packaging: 100 tablets
  • .
  • Dose: 1 tablet daily
  • .
  • Sufficient for: 100 days
  • .
Product description

The dietary supplement is a source of valuable vitamin B12 in a form that is easily absorbed by humans - cyanocobalamin. This biologically active form of vitamin B12 has many very important protective functions for the body.

Vitamin B12 supports the functioning of the immune system. It also contributes to reducing feelings of fatigue and tiredness. Its important function is also to take part in the metabolism of homocysteine, an amino acid thatós naturally formed in the human body. 

Vitamin B12 is a very important protective function.

Pros and cons

The dietary supplement is a source of valuable vitamin B12 in a form that is easily absorbed by humans - cyanocobalamin. This biologically active form of vitamin B12 has many very important protective functions for the body.

Vitamin B12 supports the functioning of the immune system. It also contributes to reducing feelings of fatigue and tiredness. Its important function is also to take part in the metabolism of homocysteine, an amino acid thatós naturally formed in the human body. 

Vitamin B12 is a very important protective function.

Additional information

The dietary supplement is a source of valuable vitamin B12 in a form that is easily absorbed by humans - cyanocobalamin. This biologically active form of vitamin B12 has many very important protective functions for the body.

Vitamin B12 supports the functioning of the immune system. It also contributes to reducing feelings of fatigue and tiredness. Its important function is also to take part in the metabolism of homocysteine, an amino acid thatós naturally formed in the human body. 

Vitamin B12 is a very important protective function.

User review

The dietary supplement is a source of valuable vitamin B12 in a form that is easily absorbed by humans - cyanocobalamin. This biologically active form of vitamin B12 has many very important protective functions for the body.

Vitamin B12 supports the functioning of the immune system. It also contributes to reducing feelings of fatigue and tiredness. Its important function is also to take part in the metabolism of homocysteine, an amino acid thatós naturally formed in the human body. 

Vitamin B12 is a very important protective function.

High dose

Aura Herbals Vitamin B Complex drops

4.8
Aura Herbals Vitamin B Complex drops
  • Active ingredients: vitamins B1, B2, B3, B5, B7, B9, B12
  • .
  • Dosage: 15 drops daily
  • .
  • Packaging size: 30 ml (60 daily servings)
  • .
  • Sufficient for: 2 months
Product description

Vegan drops with a complex of B vitamins. A daily serving covers 100% of the requirement for these vitamins. B vitamins are important for the proper functioning of the body, especially for the nervous system, metabolism and energy production.

Pros and cons

Vegan drops with a complex of B vitamins. A daily serving covers 100% of the requirement for these vitamins. B vitamins are important for the proper functioning of the body, especially for the nervous system, metabolism and energy production.

Additional information

Vegan drops with a complex of B vitamins. A daily serving covers 100% of the requirement for these vitamins. B vitamins are important for the proper functioning of the body, especially for the nervous system, metabolism and energy production.

MyBestB12Complex+

4.8
MyBestB12Complex+
  • Active ingredients:
    A complex of all B vitamins and selected adaptogens: ashwagandha and Rhodiola rosea; plant-based vitamin B12

  • For whom and why?
    For adults – supports energy levels, brain functions, the nervous system, and helps cope with stress and fatigue

  • Form:
    Vegan capsules

  • Daily dose:
    1 capsule in the morning, preferably during or after a meal; can be taken cyclically or daily

  • Sufficient for:
    30 days of use


 

Product Description

B12Complex+ MyBestPharm is a dietary supplement in capsule form, containing:

  • a composition of all 8 B vitamins: thiamine (vitamin B1), riboflavin (vitamin B2), niacin, pantothenic acid, folic acid, vitamin B6, vitamin B12, and biotin, 
  • additionally supplemented with 4 plant extractsfrom ashwagandha, rhodiola rosea, bacopa monnieri leaves, and buckwheat seeds.

The MyBestB12 Complex+ capsules are suitable for vegans as they do not contain animal-derived ingredients. The preparation uses plant-based vitamin B12 and other ingredients derived solely from plants, which are enclosed in a cellulose capsule without gelatin. 

Pros and Cons

Pros:

  • Comprehensive blend of all B vitamins + adaptogens – versatile supportive action

  • Vegan formula – free from lactose, gluten, and fillers

  • Adaptogens (ashwagandha, rhodiola rosea) help cope with stress and support brain functions

  • Convenient and easy-to-swallow capsules

  • Good user reviews – praised for energy effects and improved well-being

Cons:

  • Dietary supplement – not a medicine; consultations required for individuals with diseases or taking medications

  • Daily dose of 1 capsule – requires consistency for noticeable effects

  • Not suitable for children, pregnant or breastfeeding women without consulting a doctor

  • Time to effect – improvement in energy and mood usually noticeable after several weeks of use

Kenay Vitamin B-Complex LipoCellTech

4.7
Kenay Vitamin B-Complex LipoCellTech
  • Active ingredients:
    Liposomal complex of active vitamins B¹–B₁₂ (thiamine TPP, riboflavin-5-phosphate, B6 P-5-P, B5, biotin, methylcobalamin) and NADH, PABA, and bamboo leaf extract (source of silica).

  • For whom and why?
    For adults – supports energy levels, metabolism, the nervous system, cognitive functions, heart health, and body regeneration.

  • Form:
    Vegetarian capsules (hydroxypropyl methylcellulose), 60 pcs.

  • Daily dose:
    1 capsule between meals

  • Sufficient for:
    60 days of use

Product Description

Kenay® Vitamin B-Complex LipoCellTech is a dietary supplement containing B vitamins in a bioavailable form. The Vcaps®  capsule formula is suitable as a supplement to the daily diet of adults, especially those seeking vegan supplementation.

Pros and Cons

Pros:

  • Comprehensive formula contains all active forms of B vitamins

  • Liposomal technology (LipoCellTech): better absorption and utilisation of ingredients

  • Content of NADH and PABA enhances the synergistic action of vitamins

  • Addition of bamboo extract with silica supports tissue functions

  • Product suitable for vegans, gluten-free, lactose-free, GMO-free, preservative-free, and dye-free

Cons:

  • This is a supplement, not a medicine — medical consultation required for chronic diseases

  • One capsule daily — requires consistent use

  • Not suitable for children, pregnant or breastfeeding women without a doctor's consent

  • Higher price than basic B vitamins — but justified by form and bioavailability

Now Foods B-50

4.8
Now Foods B-50
  • Active ingredients:
    Each capsule contains 50 mg of vitamins B1 (thiamine), B2 (riboflavin), B3 (niacin), B6, B5 (pantothenic acid), 680 µg of folates (400 µg of folic acid), 50 µg of B12 (cyanocobalamin), biotin (50 µg), plus choline (50 mg), PABA (25 mg), and inositol (25 mg) – B vitamins in a form easily absorbed by the body 

  • Who is it for and why?
    For adults – supports energy production, the nervous system, homocysteine metabolism, and replenishes B-vitamin deficiencies, particularly in vegans and individuals with varied diets

  • Form:
    Vegan capsules (pullulan coating, vegan product)

  • Daily portion:
    1 capsule daily, preferably during meals

  • Sufficient for:
    100 days of use (1 package = 100 capsules)

Product Description

Now Foods B-50 is a dietary supplement in capsule form containing a complex of B vitamins. These vitamins include: thiamine, riboflavin (vitamin B2), folic acid, vitamin B6, vitamin B12, niacin, biotin, and pantothenic acid. Additionally, it is enriched with choline and inositol.

Pros and Cons

Pros:

  • Comprehensive, high doses of B vitamins along with choline, PABA, and inositol

  • Vegan formula – free from gluten, lactose, GMO, and soy

  • Supports energy production, nervous system health, and metabolism

  • Non-GMO, Kosher, Halal, GMP certifications ensure quality and safety

Cons:

  • Niacin (50 mg) may cause a "flush" (skin redness) in sensitive individuals

  • This is a supplement, not a medication – consult a doctor for health issues

  • B12 in the form of cyanocobalamin – those preferring the methylated form may seek another product

  • Biotin content may affect the results of some laboratory tests – it is advisable to inform your doctor

Naturell Витамин B Комплекс Форте

4.8
Naturell Витамин B Комплекс Форте
  • Активни съставки:
    В една таблетка: витамин B1 (3,3 mg), B2 (4,2 mg), B3 (60 mg), B5 (18 mg), B6 (4,2 mg), B7 (биотин 150 µg), B9 (фолиева киселина 600 µg) и B12 (метилкобаламин 7,5 µg) – всеки витамин представлява 300–375 % RWS.

  • За кого и за какво?
    За възрастни – особено активни физически и познавателно, стресирани, възстановяващи се и вегани – поддържа енергийния метаболизъм, нервната система, имунитета и намаляване на умората.

  • Форма:
    Вегански таблетки, без захар, лактоза, глутен и оцветители.

  • Дневна доза:
    1 таблетка, най-добре по време на хранене.

  • Достатъчно за:
    120 дни (4 месеца при дневна доза).

Описание на продукта

Naturell Витамин B Complex Forte е хранителна добавка под формата на таблетки с високо съдържание на витамини от група B: ниацин, пантотенова киселина, рибофлавин, витамин B6, тиамин, фолиева киселина, биотин и витамин B12. Комплексът от 8 витамина B е разработен с цел допълване на ежедневната диета на възрастни хора.

Плюсове и минуси

Плюсове:

  • Съдържа пълния спектър от витамини от група B в активни форми – комплексна подкрепа практически за всички метаболитни функции.

  • Метилкобаламин (форма на B12) се характеризира с по-добра бионаличност и усвояемост от организма.

  • Опаковка от 120 таблетки – икономично решение за дългосрочна добавка.

  • Продуктът е вегански и без алергени – без глутен, без лактоза и оцветители.

  • Продуктът получава много добри отзиви – средната оценка е около 4.8–4.9/5, потребителите хвалят ефективността и добрата усвояемост.

Минуси:

  • Висока доза ниацин (60 mg) може да предизвика леко „flush” (зачервяване на кожата) при чувствителни лица.

  • Това е добавка, не лекарство – при здравословни проблеми се препоръчва медицинска консултация.

  • Присъствието на фолати и B12 означава, че не трябва да се използват други добавки, съдържащи витамини от група B, без консултация с лекар.

  • Въпреки че опаковката е икономична, голямото количество таблетки изисква систематичност и подходящо съхранение.

Hauster Homocyne

4.8
Hauster Homocyne
  • Активни съставки:
    В една капсула: ниацин 500 mg, рибофлавин 50 mg, витамин B6 (P‑5‑P) 25 mg, биотин 1000 µg, метилкобаламин (B12) 300 µg, фолати под формата на 5‑MTHF (Quatrefolic®) 300 µg.

  • За кого и за какво?
    За възрастни – помага за поддържане на нормално ниво на хомоцистеин в кръвта, което е важно за профилактика на сърдечно-съдови заболявания. Препоръчва се при повишено ниво на хомоцистеин, недостиг на фолати и при хора с мутация на гена MTHFR – особено в страни с висок дял на тази мутация.  

  • Форма:
    Растителни капсули с l‑левцин и инулин – подходящи за вегани, без изкуствени добавки и пълнители, в стъклено опаковане. 

  • Дневна доза:
    1 капсула дневно.

  • Достатъчно за:
    120 дни употреба при препоръчителна доза.

Homocyne® е хранителна добавка, която е концентриран източник на кофактори. Специално подбраната формула на препарата представлява комбинация от най-добре усвоими, биоактивни форми на витамини, включително патентованата активна форма на фолиева киселина, а именно (6S)-5-Methyltetrahydrofolic (5-MTHF) Quatrefolic®, допълнена с ниацин, рибофлавин, витамин B6, B12 и биотин в високи дози.

Плюсове и минуси

Плюсове:

  • Комплекс от витамини B в активни форми, включително метилкобаламин и 5‑MTHF – максимална бионаличност

  • Висока доза кофактори за метаболизма на хомоцистеина – ефективна подкрепа

  • Подходящ за вегани, свободен от ГМО, лактоза, глутен, консерванти и оцветители

  • Стъклена опаковка – екологична и безопасна за съдържанието

  • Препоръчва се при риск от хиперхомоцистеинемия и сърдечно-съдови заболявания

Минуси:

  • Много високи дози витамини B – могат да предизвикат силен „flush“ (зачервяване на кожата), особено при чувствителни на ниацин

  • Добавка, не лекарство – изисква консултация с лекар при хронични заболявания или прием на други лекарства

  • Не се препоръчва за бременни и кърмещи жени – не използвайте без консултация

  • Ефектите изискват дългосрочна терапия (няколко седмици) и мониторинг на нивото на хомоцистеина чрез изследвания

  • Поради високата доза, приемането на повече от 1 капсула на ден изисква внимание

Vitamin B1 requirement

.

Adequate vitamin concentrations are the basis for a healthy body. How much thiamine do we need each dayand?

.

Age

.

Daily thiamine requirement* 

.

0-6 months

0.2 mg

7-11 months

0.3 mg

1-3 years

0.5 mg

4-6 years

0.6 mg

7-9 years

0.9 mg

10-12 years

1 mg

13-18 years old girls

1.1 mg

13-18 years old boys

1.2 mg

Females

1.1 mg

Males

1.3 mg

*Nutrition standards for the Polish population

.

The requirement for vitamin B1 increases during pregnancy and breastfeeding. When you are expecting a baby, you should take 1.4 mg of thiamine per day. Conversely, during breastfeeding, the requirement for vitamin B1 is even higher at 1.5 mgand.

.
The human body has deposits of vitamin B1 that last for about 3 months
.
Julia Skrajda.

Julia SkrajdaDietitian

.
.

Sources of thiamine

.

Thiamine should be supplied to the body with the diet. Healthy meals are the key to a healthy body. In which products can we find vitamin B1and?

.

Product

.

Thiamine content per 100 grams

.
.

Rice bran

2,750 mg

.

Flax seed

1,640 mg

.

Dried sunflower seeds

1,480 mg

.

Hemp seeds

1,280 mg

Dried coriander

1,250 mg

Oat bran

1,170 mg

.

Salami

0.930 mg

Dried chives

0.900 mg

Poppy seeds

0.854 mg

Pork tenderloin

.

0.765 mg

.
.
Research suggests that vitamin B1 has a high association with migraine. A diet rich in this vitamin was associated with a lower incidence of migraines, especially among women.
Julia Skrajda.

Julia SkrajdaDietitian

.
.

.

Vitamin B1 deficiency

.

Thiamine deficiency in developed countries is a rare occurrence. However, specific groups of people may be particularly vulnerable to vitamin B1 deficiency in the body.

What affects thiamine deficiencyand?

  • AIDS/HIV.

    .
  • Alcohol addiction alcohol dependence.

  • AIDS/HIV.

  • Inappropriate diet. 

  • Taking certain medications.

  • Long-term parenteral nutrition.

  • Prolonged diarrhoea.

  • Prolonged diarrhoea.

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Coffee, tea and seafood reduce the absorption of vitamin B1. People who are trying to supplement a deficiency of this vitamin should not consume these foods in large quantities.
Julia Skrajda.

Julia SkrajdaDietitian

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Symptoms

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Symptoms of thiamine deficiency can be easily overlooked. They are most often vague and mimic signs of other conditions. Which ones should raise our concern?

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Fatigue

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Thiamine is essential in the production of energy, which is why its deficiency can manifest as fatigue. The first signs can appear as early as a few weeks after a deficiency. Although fatigue can be a symptom of many conditions, numerous studies have linked it specifically to vitamin B1 deficiencyand.

Greater mood

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Vitamin B1 deficiency leads to sudden changes in mood. Its lack in the body can manifest as irritability or feelings of irritability. Interestingly, this symptom is also indicative of thiamine deficiency in infantsand.

Tingling in arms and legs

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Tingling in the limbs can be a symptom of a deficiency of vitamin B1. Thiamine is essential for the proper functioning of the nerves. Therefore, a lack of it leads to paresthesia - tingling in the arms and legs. In the long term, this can result in damage to the peripheral nervesand.

Blurred vision

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Thiamine deficiency also affects vision. It manifests as swelling of the optic nerve, leading to blurred vision. Supplementation of vitamin B1 in such cases significantly improves vision. Furthermore, preliminary animal studies suggest that thiamine intake may prevent the visual damage caused by alcoholand.

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A symptom of vitamin B1 deficiency is reduced blood pressure.
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Julia Skrajda.

Julia SkrajdaDietitian

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Omega acids, especially omega-3 also affect eye health. I invite you to check out these articles!

What are the other symptoms of thiamine deficiencyand?

  • Problems with logical thinking.

  • Loss of short-term memory.

  •  
  • Loss of short-term memory.
  • Diffidence.

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Symptoms of vitamin B1 deficiency include loss of appetite, fatigue, muscle weakness, irritability, impaired reflexes, tingling in the upper and lower extremities, decreased vision, changes in heart rate, and even nausea or vomiting.
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Carolina Król-LachDietitian

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Vitamin B1 deficiency disease - beri-beri

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Beri-beri is a disease caused by vitamin B1 deficiency. Its most common cause is a lack of a balanced diet. There are two types of beri-beri diseaseand:

    • Wet. Affects the heart and circulatory system. In extreme cases, it can lead to heart failure.

    • Dryness. Damages nerves and reduces muscle strength. If left untreated in the long term, it can even result in paralysis.

    • Sickness.

Beri-beri disease is diagnosed using blood and urine tests. Doctors also perform neurological examinations for this purpose. Treatment of beri-beri is most often through supplementation monitored by a specialist.

Treatment of beri-beri is usually by supplementation monitored by a specialist.

Excess vitamin B1

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The body excretes excess thiamine with urine. Consumption of vitamin B1 in doses as high as 50 mg per day has not caused side effects.and 

This is why a maximum daily dose of thiamine has not been established. This is most likely due to the fact that the absorption of vitamin B1 at doses above 5 mg, is significantly reduced by our body .

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With chronic use of vitamin B1 above 3000 mg per day, symptoms of toxicity can occur. These include headache, irritability, insomnia, weakness, tachycardia and allergic reactions.
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Carolina Król-LachDietitian

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Tiamine supplementation

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Want to replace a healthy diet with supplements? Forget it! It is balanced meals that influence our health. Sometimes, however, it is necessary to "top up" the vitamin B1 requirement. The exceptions to this are extreme deficiencies. Then supplements are advisable.

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How long to take?

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The length of supplementation depends on the doctor's recommendations. In cases of severe deficiency, very high doses may be taken - either orally or by injection. This can reduce the deficiency symptoms associated with the heart within days or even hours. In contrast, reversing the effects of thiamine deficiency related to the nervous system or brain, can take up to three to six monthsand.

Contraindications

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Vitamin B1, like all other vitamins for the general public, is safe. However, if you have had allergic reactions involving it, ask your doctor's opinion before starting supplementation. Furthermore, people with any medical conditions or who are allergic to certain ingredients in supplements should also seek advice from a specialist.

Morning or evening?

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Thiamine, like pantothenic acid, folate or vitamin B3, is a water-soluble vitamin. This is why it is a good idea to take it in the morning, on an empty stomach. The best time to do this is about half an hour before your first meal. However, if you do not have this option, take vitamin B1 at any time of the day.

Vitamin B1 in pregnancy

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Vitamin B1 influences the health of pregnancy. It supports the development of the baby and also helps to convert carbohydrates into energy. It affects the function of the nervous system and the heart. Furthermore, thiamine deficiency negatively affects the development of cognitive functions in the yet unborn child. The recommended dose of thiamine for pregnant women is 1.4 mg per dayand.

Thiamine and breastfeeding

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The breastfeeding period, like pregnancy, is governed by its own rules. The need for thiamine is higher then (1.5 mg per day), and a deficiency will translate into a lack of vitamin B1 in the infant's body. The result, will be gastrointestinal symptoms, heart failure or lactic acidosisand.

Vitamin B1 and alcohol

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Alcoholism leads to impaired absorption of thiamine from the gut. Therefore, people who abuse alcoholic beverages are at risk of vitamin B1 deficiency. The result can be serious problems with brain function, cognitive function, memory, intellect or personalityand.

Furthermore, long-term alcohol consumption leads to Korsakov syndrome. It manifests as amnesia and cognitive impairment.

Interactions of thiamine with drugs

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It has not been established with which drugs vitamin B1 interacts. However, some agents can affect its concentration. This is primarily furosemide, a diuretic drug that lowers blood pressure. Some chemotherapy drugs can also adversely affect thiamine concentrationsand.

See also:

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Summary

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Remember:

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  • Vitamin B1 is a water-soluble vitamin responsible for the function of the body's cells.
  • Aiding the fight against depression, preventing nerve diseases or increasing energy production are just some of the properties of thiamine.
  • Thiamine is a vitamin that is responsible for the functioning of the body's cells.
  • The daily requirement of vitamin B1 is 1.1 mg for women and 1.3 mg for men.
  • .
  • Most thiamine can be found in rice bran, flax seeds and dried sunflower seeds.
  • .
  • Deficiency of vitamin B1 manifests itself as mood deterioration or fatigue, and in the long term leads to the dangerous disease beri-beri.
  • .
  • Excess thiamine is excreted in the urine.
  • .
  • Vitamin B1 is crucial for the health of pregnancy.
  • .
  • Alcohol abuse negatively affects thiamine levels in the body.
  • .

FAQ

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. What impairs the absorption of vitamin B1? .

Antibiotics, hormonal contraceptives and some antacids, as well as excess caffeine, impair vitamin B1 absorption.

In contrast, the addition of vitamin C, vitamin E, the vitamins B2 and B3, as well as manganese and magnesium improve the bioavailability of this vitamin.

. What does vitamin B1 help with? .

Vitamin B1, or thiamine, is one of the water-soluble B vitamins and is responsible for many processes in our body. It is involved in metabolic and biochemical changes, influences cell growth and development, neutralises free radicals and supports nervous system function.

. Is excess vitamin B1 harmful? .

Excess vitamin B1 is excreted in the urine, so it is difficult to overdose. Prolonged intake of high doses of vitamin B1 can cause muscle tremors, arrhythmia, dizziness and allergic reactions.

. Which vitamins to take for stress and nerves? .

Vitamin B1 supports memory and concentration, helps fight migraine pains, and stabilises mood. It's also worth reaching for riboflavin and niacin - they provide energy comfort for brain cells, minimise the risk of depressive states and low mood. Also check out the best tranquilliser tablets if needed.

. What are the symptoms of vitamin B1 deficiency? .

Vitamin B1 deficiency can manifest as fatigue, mood deterioration, tingling in the limbs, impaired vision, problems with logical thinking and concentration, as well as shortness of breath and nausea. Supplementation with vitamin B1 to reverse the serious effects of deficiency can take 3 to 6 months.

. Where is the most vitamin B1 available? .

The best sources of vitamin B1 are rice and oat bran, flax and sunflower seeds, whole grain bread, duck and goose meat, pork and legumes. If you want to supplement deficiencies or have an increased need for vitamin B1, consider supplementation, and discuss the dose with your doctor or nutritionist.

. What destroys vitamin B1? .

Vitamin B1 is broken down by thiaminase, an enzyme contained in raw fish and shellfish, among other things. Fortunately, heat treatment is sufficient for thiaminases to no longer be harmful to us.

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Sources

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. See all .

Abdollahifard, S., Rahmanian Koshkaki, A., & Moazamiyanfar, R. (2014). The effects of vitamin B1 on ameliorating the premenstrual syndrome symptoms. Global Journal of Health Science, 6(6), 144-153. https://doi.org/10.5539/gjhs.v6n6p144

Calderón-Ospina, C. A., & Nava-Mesa, M. O. (2019). B Vitamins in the nervous system: Current knowledge of the biochemical modes of action and synergies of thiamine, pyridoxine, and cobalamin. CNS Neuroscience & Therapeutics, 26(1), 5-13. https://doi.org/10.1111/cns.13207

Costantini, A., Pala, M. I., Catalano, M. L., Notarangelo, C., & Careddu, P. (2014). High-Dose Thiamine Improves Fatigue After Stroke: A Report of Three Cases. The Journal of Alternative and Complementary Medicine, 20(9), 683-685. https://doi.org/10.1089/acm.2013.0461

Dias, F. M. V., Silva, D. M. de F., Doyle, F. C. de P., & Ribeiro, A. M. (2013). The connection between maternal thiamine shortcoming and offspring cognitive damage and poverty perpetuation in underprivileged communities across the world. Medical Hypotheses, 80(1), 13-16. https://doi.org/10.1016/j.mehy.2012.09.011

Eshak, E. S., & Arafa, A. E. (2018). Thiamine deficiency and cardiovascular disorders. Nutrition, Metabolism, and Cardiovascular Diseases: NMCD, 28(10), 965-972. https://doi.org/10.1016/j.numecd.2018.06.013

Hammond, N., Wang, Y., Dimachkie, M. M., & Barohn, R. J. (2013). Nutritional Neuropathies. Neurologic Clinics, 31(2), 477-489. https://doi.org/10.1016/j.ncl.2013.02.002

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Huertas-González, N., Hernando-Requejo, V., Luciano-García, Z., & Cervera-Rodilla, J. L. (2015). Wernicke's Encephalopathy, Wet Beriberi, and Polyneuropathy in a Patient with Folate and Thiamine Deficiency Related to Gastric Phytobezoar. Case Reports in Neurological Medicine, 2015, e624807. https://doi.org/10.1155/2015/624807

Kloss, O., Eskin, N. A. M., & Suh, M. (2018). Thiamin deficiency on fetal brain development with and without prenatal alcohol exposure. Biochemistry and Cell Biology, 96(2), 169-177. https://doi.org/10.1139/bcb-2017-0082

Moulin, P., Cinq-Frais, C., Gangloff, C., Peyre, M., Seguela, P.-E., Charpentier, S., Cascarigny, F., Alcouffe, F., Periquet, B., Dulac, Y., & Acar, P. (2014). Béribéri du nourrisson: À propos d'un cas. Archives de Pédiatrie, 21(4), 392-395. https://doi.org/10.1016/j.arcped.2014.01.009

Office of Dietary Supplements-Thiamin. (n.d.). Retrieved 17 March 2023, from https://ods.od.nih.gov/factsheets/Thiamin-HealthProfessional/

Roda, M., di Geronimo, N., Pellegrini, M., & Schiavi, C. (2020). Nutritional Optic Neuropathies: State of the Art and Emerging Evidences. Nutrients, 12(9), Article 9. https://doi.org/10.3390/nu12092653

Rolfe, M. (1994). Beri-beri: 'Endemic among urban Gambians'. Africa Health, 16(3), 22-23.

Staff, N. P., & Windebank, A. J. (2014). Peripheral Neuropathy Due to Vitamin Deficiency, Toxins, and Medications. Continuum : Lifelong Learning in Neurology, 20(5 Peripheral Nervous System Disorders), 1293-1306. https://doi.org/10.1212/01.CON.0000455880.06675.5a

Ucak, T., Karakurt, Y., Tasli, G., Cimen, F. K., Icel, E., Kurt, N., Ahiskali, I., & Süleyman, H. (2019). The effects of thiamine pyrophosphate on ethanol-induced optic nerve damage. BMC Pharmacology and Toxicology, 20(1), 40. https://doi.org/10.1186/s40360-019-0319-5

Wet beriberi with multiple organ failure remarkably reversed...: Medicine. (n.d.). Retrieved March 17, 2023, from https://journals.lww.com/md-journal/fulltext/2018/03020/wet_beriberi_with_multiple_organ_failure.4.aspx

Wiley, K. D., & Gupta, M. (2022). Vitamin B1 Thiamine Deficiency. In StatPearls. StatPearls Publishing. http://www.ncbi.nlm.nih.gov/books/NBK537204/

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Ludwik Jelonek - Author

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Ludwik Jelonek

Ludwik Jelonek is the author of more than 2,500 texts published on leading portals. His content has found its way into services such as Ostrovit and Kobieta Onet. At Natu.Care, Ludwik educates people in the most important area of life - health.

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Clinical nutritionist

Julia Skrajda
Verified by an expert

A clinical nutritionist, she works in the profession and creates personalised menus and recommendations for disease entities.

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Editor

Michael Tomaszewski

Graduate of Journalism and Artes Liberales at the University of Warsaw. Since 2017, he has been working with the biggest portals in Poland and abroad as an editor. Previously worked for 3 years in one of the leading pharmaceutical companies - he knows the health and beauty industry inside out. In his free time, he most enjoys playing tennis or skiing.

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Emilia Moskal

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