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Lyophilised or hydrolysed collagen? Opinions

Does freeze-dried fish collagen perform better than hydrolysate?

Matthew Podlecki - AuthorAuthorMatthew Podlecki
Matthew Podlecki - Author
AuthorMatthew Podlecki
Natu.Care Editor

At Natu.Care, she educates about healthy lifestyles and debunks dangerous myths, contrasting them with the results of the latest scientific research. Additionally, she is interested in new technologies and their impact on health and everyday life.

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Ilona Bush - Reviewed byReviewed byIlona Bush
Verified by an expert
Ilona Bush - Reviewed by
Reviewed byIlona Bush
Master of Pharmacy

Ilona Krzak obtained her Master of Pharmacy degree from the Medical University of Wrocław. She did her internship in a hospital pharmacy and in the pharmaceutical industry. She is currently working in the profession and also runs an educational profile on Instagram: @pani_z_apteki

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Bartholomew Turczynski - Edited byEdited byBartholomew Turczynski
Bartholomew Turczynski - Edited by
Edited byBartholomew Turczynski
Editor-in-Chief

Bartłomiej Turczyński is the editor-in-chief of Natu.Care. He is responsible for the quality of the content created on Natu.Care, among others, and ensures that all articles are based on sound scientific research and consulted with industry specialists.

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Ludwig Jelonek - Fact-checkingFact-checkingLudwig Jelonek
Ludwig Jelonek - Fact-checking
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Ludwik Jelonek is the author of more than 2,500 texts published on leading portals. His content has found its way into services such as Ostrovit and Kobieta Onet. At Natu.Care, Ludwik educates people in the most important area of life - health.

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Lyophilised or hydrolysed collagen? Opinions
29 April, 2024
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Liophilised snacks are great for mountain trails, and chocolates with freeze-dried fruit are a hit with many confectioners. But is freeze-dried collagen ok?

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I will tell you about it together with pharmacist and educator Ilona Krzak. We'll look at how it differs from other forms and whether it's worth reaching for in collagen supplementation.

We'll look at how it differs from other forms and whether it's worth reaching for in collagen supplementation.

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From this article you will learn:

  • What is freeze-dried collagen.
  • .
  • What to choose: freeze-dried fish collagen or hydrolysate.
  • Why it is more common to use freeze-dried collagen.
  • Why hydrolysed collagen is more commonly used.
  • .

See also:

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What is freeze-dried collagen?

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Lyophilised collagen is a form of collagen from which water has been completely removed, without disturbing its delicate structure - making it almost identical to that found in our bodies. Freeze-dried collagen is stable, dry and easy to store.

Liophilised collagen is often used as a base for dietary supplements, as it is very well absorbed by the body in this form - much better than natural collagen.

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Because of the loss of water, freeze-dried collagen is more concentrated. There will be less pure collagen in 100g of natural collagen than in 80g of freeze-dried.
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Ilona Krzak.

Ilona Krzak Master of Pharmacy

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Scientific research shows that collagen supplementation can improve skin elasticity, reduce wrinkles and promote connective tissue regeneration and is a sensible way to supplement collagen deficiency.

What is the freeze-drying process and how does it affect collagen?

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Liophilisation, or sublimation, removes water from collagen. In the shortest terms, freeze drying is "drying by freezing" (freeze drying). You're familiar with those raspberry flecks in your favourite granola? They are freeze-dried.

The whole process consists of three main steps:

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  • Freezing - when exposed to very low temperatures (around -50 °C), the water in the collagen freezes;
  • .
  • Primary drying - in a vacuum chamber and under low pressure, the frozen ice begins to sublimate, i.e. it turns immediately into water vapour (bypassing the liquid state);
  • .
  • Secondary drying - residual water is removed to produce a dry, fully stable powder;
  • .

Collagen, like those granola raspberries, remains chemically intact and retains its natural properties.

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The freeze-drying process yields so-called collagen sponges, which are used in medicine as dressing agents. They are excellent at absorbing exudates. They are biocompatible and hypoallergenic.
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Ilona Krzak.

Ilona Krzak Master of Pharmacy

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These are a few products that contain freeze-dried fish collagen.

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Colafit Pure crystalline collagen

Colafit Pure crystalline collagen
4.2
  • Collagen content: 8 mg freeze-dried collagen (corresponds to a dose of 800 mg collagen)
  • .
  • Additional active ingredients: none
  • .
  • Form: cubes
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  • Dosage:one cube per day
  • .
  • Sufficient for: 120 days
  • .
See price
in the i-Apteka.pl shop
Product description

The supplement in the form of small, soft and tasteless cubes is easy to supplement. It will benefit the appearance of the skinóry, hairóry and nails. It can helpóc keep joints and ligaments in good condition.

Pros and cons

The supplement in the form of small, soft and tasteless cubes is easy to supplement. It will benefit the appearance of the skinóry, hairóry and nails. It can helpóc keep joints and ligaments in good condition.

Additional information

The supplement in the form of small, soft and tasteless cubes is easy to supplement. It will benefit the appearance of the skinóry, hairóry and nails. It can helpóc keep joints and ligaments in good condition.

User review

The supplement in the form of small, soft and tasteless cubes is easy to supplement. It will benefit the appearance of the skinóry, hairóry and nails. It can helpóc keep joints and ligaments in good condition.

DacomPharma Colafit

DacomPharma Colafit
4.2
  • Collagen content: 8 mg freeze-dried collagen type 1 (corresponds to a dose of 800 mg of collagen)
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  • Additional active ingredients: none
  • .
  • Form: cubes
  • .
  • Dosage:one cube per day
  • .
  • Sufficient for: 60 days
  • .
See price
in the i-Apteka.pl shop
Product description

Pure collagen in the form of freeze-dried collagen closed in small, soft cubes whichór do not need to be drunk with water. The supplement will help you supplement collagen deficiencies in your diet, which will have a beneficial effect on your musculoskeletal system and the appearance of your skin.

Pros and cons

Pure collagen in the form of freeze-dried collagen closed in small, soft cubes whichór do not need to be drunk with water. The supplement will help you supplement collagen deficiencies in your diet, which will have a beneficial effect on your musculoskeletal system and the appearance of your skin.

Additional information

Pure collagen in the form of freeze-dried collagen closed in small, soft cubes whichór do not need to be drunk with water. The supplement will help you supplement collagen deficiencies in your diet, which will have a beneficial effect on your musculoskeletal system and the appearance of your skin.

Elena Collagenum Francis capsules

Elena Collagenum Francis capsules
3.9
  • Collagen content: 125 mg fish collagen
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  • Additional active ingredients: goat's and mare's milk, chokeberry fruit, cranberry fruit
  • Form: capsules
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  • Dose: 2–4 capsules daily
  • .
  • Sufficient for: 30 or 60 days
  • .
See price
in the Empik shop
Product description

Liophilised fish collagen has been enriched with two types of freeze-dried milk and fruitós. It will positively influence the appearance of your skinóry and allow it to retain its youthfulness for a longer time.

Pros and cons

Liophilised fish collagen has been enriched with two types of freeze-dried milk and fruitós. It will positively influence the appearance of your skinóry and allow it to retain its youthfulness for a longer time.

Additional information

Liophilised fish collagen has been enriched with two types of freeze-dried milk and fruitós. It will positively influence the appearance of your skinóry and allow it to retain its youthfulness for a longer time.

Elena Kolagenum Franciszka Lyophilised collagen powder

Elena Kolagenum Franciszka Lyophilised collagen powder
4.2
  • Collagen content: 500 mg of fish collagen in freeze-dried form
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  • Additional active ingredients: goat's and mare's milk, strawberries, raspberries, cranberries
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  • Form: powder
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  • Dosage: 1 sachet every other day
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  • Sufficient for: 30 days
  • .
See price
in the Empik shop
Product description

Liophilised fish collagen in convenient powder sachets to dissolve in water. The supplement will help supplement your diet with collagen.

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Pros and cons

Liophilised fish collagen in convenient powder sachets to dissolve in water. The supplement will help supplement your diet with collagen.

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Additional information

Liophilised fish collagen in convenient powder sachets to dissolve in water. The supplement will help supplement your diet with collagen.

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See also:

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Which collagen is better - freeze-dried or hydrolysed? Which to choose?

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Battling with thoughts, what collagen to choose - freeze-dried or hydrolysed? Both will behave almost identically when ingested in your body.

The final choice is down to your personal preference.

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Why? After ingestion, freeze-dried collagen - as a result of digestion - is broken down into individual amino acids. This is similar to what happens during hydrolysis, i.e. collagen is broken down into smaller molecules (peptides).

Hydrolysed collagen is broken down into smaller molecules (peptides).

Collagen hydrolysate peptides pass easily through the digestive tract and are well absorbed, allowing your body - from single amino acids - to rebuild collagen molecules to be used in other tissues.

In the body, both forms of supplements - lyophilised and hydrolysed collagen - behave similarly.

In simple terms, we can assume that hydrolysed collagen is pre-digested. Lyophilisate is not. And this is where the two camps collide: 'hydrolysate is better because it requires less effort from your body to digest it' versus 'freeze-dried is better because it's less processed'.

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Some collagen peptides have biological activity, such as being anti-inflammatory or serving as so-called signal molecules. We are not always able to obtain this in the process of collagen digestion, as it depends on the enzymes which peptides it breaks down into.
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Ilona Krzak.

Ilona Krzak Master of Pharmacy

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Today there are no studies that have tipped the scales in favour of one or the other and it is akin to arguing about whether carrots are better eaten whole or cut into pieces.

The freeze-drying process, however, is much more expensive and time-consuming, so you will pay more for products with freeze-dried collagen than those with hydrolysate. The latter additionally dissolves better, which is important if you like to make yourself a healthy drink or workout shake from time to time.

See also:

Do type, form and form of collagen matter in collagen intake?

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After you pass the magic age limit of 25, your body's collagen production starts to decline, with less each year and not enough to meet all your needs. Collagen supplementation seems natural. Flabby skin, thin thinning hair, brittle nails, and something starts to crunch in the joints too.

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The thought of supplementation seems perfectly normal.

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When buying a collagen supplement, other considerations will be more important:

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  • Purpose of supplementation and type of collagen: type I collagen and III have more of an effect on hair, skin and nails, while type 2 collagen has more of an effect on joints.
  • Origin - decide whether you prefer fish collagen (sea collagen), beef collagen, pork collagen, poultry collagen or maybe some other. Fish collagen is most similar to human collagen.
  • .
  • Form - you can choose primarily from powdered collagen, drinkable collagen, collagen in tablets or capsules and liquid collagen.
  • .
  • Position - it matters whether you take natural collagen, collagen hydrolysate or perhaps freeze-dried collagen; whether it is powdered animal cartilage or, however, biologically active peptides. Consider that hydrolysates have smaller particles, so are better absorbed.
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  • Dose - research suggests that a dose of 2500-15000 mgand is safe for long-term use. The optimal daily requirement is around 4000-5000 mg. Collagen is difficult to overdose on, however, it is definitely better to take 10000 mg than just 200 or 400 mg. Here you will see the full criteria.
  • .

Unfortunately, you will find many products on the market that promise a lot, tempt you with beautiful packaging, while inside you will find tablets, capsules or sachets in which there will be at most 100 or 300 mg of collagen.

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Here are some of our suggestions for formulations with hydrolysed collagen that you might consider:

Best overall

Natu.Care Collagen Premium 5000 mg, mango-maracuja

Natu.Care Collagen Premium 5000 mg, mango-maracuja
5.0
  • Collagen content: 5000 mg marine collagen hydrolysate
  • .
  • Additional active ingredients: vitamin C, low molecular weight hyaluronic acid (and L-theanine and coenzyme Q10 in cocoa flavoured collagen or vitamin A and vitamin E in mango–passion fruit flavoured collagen)
  • .
  • Form: powder sachets
  • .
  • Dose: 1 sachet per day
  • .
  • Sufficient for: 30 days
  • .
See price
in the Natu.Care shop
Product description

Fish collagen from the Natu.Care brand in a dose of 5000 mg, based on certified ingredients of the best quality. Regular supplementation will positively influence the appearance of the skinóry, hairów and nails – they will be rebuilt and strengthened from the inside.

In addition to collagen, which is valuable for health and beauty, it also offers other active ingredients that help to maintain a youthful complexion, shiny hair and strong nails.

The formula contains a sufficient portion of the active ingredient to positively affect joints, the musculoskeletal system and immunity.

Natu.Care Premium Collagen is available in two flavours – Cacao Bloom and Rise&Shine. Both formulas are based on the following active ingredients: marine collagen hydrolysate, wild roseóbud extract and hyaluronic acid.

Additionally, Cacao Bloom contains natural L-theanine, coenzyme Q10 and defatted Dutch cacao. Rise&Shine instead contains vitamin E and vitamin A.

These are the best collagens in the world.

These best fish collagens on the market also rós taste – Cacao Bloom is a treat for chocolate lovers. Rise&Shine will appeal to those whoólike the refreshing taste of mangoófruit and passion fruit.

Pros and cons

Fish collagen from the Natu.Care brand in a dose of 5000 mg, based on certified ingredients of the best quality. Regular supplementation will positively influence the appearance of the skinóry, hairów and nails – they will be rebuilt and strengthened from the inside.

In addition to collagen, which is valuable for health and beauty, it also offers other active ingredients that help to maintain a youthful complexion, shiny hair and strong nails.

The formula contains a sufficient portion of the active ingredient to positively affect joints, the musculoskeletal system and immunity.

Natu.Care Premium Collagen is available in two flavours – Cacao Bloom and Rise&Shine. Both formulas are based on the following active ingredients: marine collagen hydrolysate, wild roseóbud extract and hyaluronic acid.

Additionally, Cacao Bloom contains natural L-theanine, coenzyme Q10 and defatted Dutch cacao. Rise&Shine instead contains vitamin E and vitamin A.

These are the best collagens in the world.

These best fish collagens on the market also rós taste – Cacao Bloom is a treat for chocolate lovers. Rise&Shine will appeal to those whoólike the refreshing taste of mangoófruit and passion fruit.

Additional information

Fish collagen from the Natu.Care brand in a dose of 5000 mg, based on certified ingredients of the best quality. Regular supplementation will positively influence the appearance of the skinóry, hairów and nails – they will be rebuilt and strengthened from the inside.

In addition to collagen, which is valuable for health and beauty, it also offers other active ingredients that help to maintain a youthful complexion, shiny hair and strong nails.

The formula contains a sufficient portion of the active ingredient to positively affect joints, the musculoskeletal system and immunity.

Natu.Care Premium Collagen is available in two flavours – Cacao Bloom and Rise&Shine. Both formulas are based on the following active ingredients: marine collagen hydrolysate, wild roseóbud extract and hyaluronic acid.

Additionally, Cacao Bloom contains natural L-theanine, coenzyme Q10 and defatted Dutch cacao. Rise&Shine instead contains vitamin E and vitamin A.

These are the best collagens in the world.

These best fish collagens on the market also rós taste – Cacao Bloom is a treat for chocolate lovers. Rise&Shine will appeal to those whoólike the refreshing taste of mangoófruit and passion fruit.

User review

Fish collagen from the Natu.Care brand in a dose of 5000 mg, based on certified ingredients of the best quality. Regular supplementation will positively influence the appearance of the skinóry, hairów and nails – they will be rebuilt and strengthened from the inside.

In addition to collagen, which is valuable for health and beauty, it also offers other active ingredients that help to maintain a youthful complexion, shiny hair and strong nails.

The formula contains a sufficient portion of the active ingredient to positively affect joints, the musculoskeletal system and immunity.

Natu.Care Premium Collagen is available in two flavours – Cacao Bloom and Rise&Shine. Both formulas are based on the following active ingredients: marine collagen hydrolysate, wild roseóbud extract and hyaluronic acid.

Additionally, Cacao Bloom contains natural L-theanine, coenzyme Q10 and defatted Dutch cacao. Rise&Shine instead contains vitamin E and vitamin A.

These are the best collagens in the world.

These best fish collagens on the market also rós taste – Cacao Bloom is a treat for chocolate lovers. Rise&Shine will appeal to those whoólike the refreshing taste of mangoófruit and passion fruit.

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Pure collagen

Natu.Care Collagen 3000 mg, tasteless

Natu.Care Collagen 3000 mg, tasteless
4.6
  • Collagen content: 3000 mg collagen hydrolysate fish
  • Additional active ingredients: none
  • .
  • Form: powder
  • .
  • Dose: one scoop per day
  • .
  • Sufficient for: 30 days
  • .
See price
in the Natu.Care shop
Product description

The dietary supplement contains only pure fish collagen in the formula SeaGarden®. This Norwegian collagen is characterised by its purity and high bioavailability, which means that youróy body will utilise the collagen faster and more effectively.

Regular supplementation fish collagen benefits hair, skinóhand and nails and supports joints, muscles and bones. It improves the appearance of the skinóry and slows down its ageing, giving it a healthy glow.

Natu.Care Collagen 3000 mg has a neutral taste, dissolves well, does not form lumps in liquid and you can add it to your drink, yoghurt or smoothie.

Pros and cons

The dietary supplement contains only pure fish collagen in the formula SeaGarden®. This Norwegian collagen is characterised by its purity and high bioavailability, which means that youróy body will utilise the collagen faster and more effectively.

Regular supplementation fish collagen benefits hair, skinóhand and nails and supports joints, muscles and bones. It improves the appearance of the skinóry and slows down its ageing, giving it a healthy glow.

Natu.Care Collagen 3000 mg has a neutral taste, dissolves well, does not form lumps in liquid and you can add it to your drink, yoghurt or smoothie.

Additional information

The dietary supplement contains only pure fish collagen in the formula SeaGarden®. This Norwegian collagen is characterised by its purity and high bioavailability, which means that youróy body will utilise the collagen faster and more effectively.

Regular supplementation fish collagen benefits hair, skinóhand and nails and supports joints, muscles and bones. It improves the appearance of the skinóry and slows down its ageing, giving it a healthy glow.

Natu.Care Collagen 3000 mg has a neutral taste, dissolves well, does not form lumps in liquid and you can add it to your drink, yoghurt or smoothie.

Aura Herbals Colladrop Forte

Aura Herbals Colladrop Forte
4.5
  • Collagen content: 10,000 mg sea collagen
  • Additional active ingredients: vitamin C and coenzyme Q10
  • Form: sachets of powder
  • .
  • Dosage: one sachet per day
  • .
  • Sufficient for: 30 days
  • .
See price
in the Natu.Care shop
Product description

A dietary supplement containing fish collagen for drinking in a high dose of 10,000 mg hydrolysate. It also offers you additional health and beauty benefits thanks to its coenzyme Q10 and vitamin C content. Supplementation with collagen can improve the appearance of your skinóskin, hairónails and improve the function of your jointsómuscles and bones.

Pros and cons

A dietary supplement containing fish collagen for drinking in a high dose of 10,000 mg hydrolysate. It also offers you additional health and beauty benefits thanks to its coenzyme Q10 and vitamin C content. Supplementation with collagen can improve the appearance of your skinóskin, hairónails and improve the function of your jointsómuscles and bones.

Additional information

A dietary supplement containing fish collagen for drinking in a high dose of 10,000 mg hydrolysate. It also offers you additional health and beauty benefits thanks to its coenzyme Q10 and vitamin C content. Supplementation with collagen can improve the appearance of your skinóskin, hairónails and improve the function of your jointsómuscles and bones.

Aura Herbals Colladrop Flex

Aura Herbals Colladrop Flex
4.4
  • Collagen content: 5000 mg marine collagen
  • .
  • Additional active ingredients: vitamin Chyaluronic acidvitamin K1, vitamin D2
  • Form: sachets of powder
  • .
  • Dose: 1 sachet daily
  • .
  • Sufficient for: 30 days
  • .
See price
in the Natu.Care shop
Product description

Fish collagen in sachets for joint healthós and wrinkle reduction with the addition of numerous active ingredientsós including vitamin C, hyaluronic acid and vitamin K1 and rare vitamin D2.

Pros and cons

Fish collagen in sachets for joint healthós and wrinkle reduction with the addition of numerous active ingredientsós including vitamin C, hyaluronic acid and vitamin K1 and rare vitamin D2.

Additional information

Fish collagen in sachets for joint healthós and wrinkle reduction with the addition of numerous active ingredientsós including vitamin C, hyaluronic acid and vitamin K1 and rare vitamin D2.

User review

Fish collagen in sachets for joint healthós and wrinkle reduction with the addition of numerous active ingredientsós including vitamin C, hyaluronic acid and vitamin K1 and rare vitamin D2.

Sundose° For Skin Anti-Aging°

Sundose° For Skin Anti-Aging°
4.8
  • Collagen content: 5000 mg of collagen hydrolysate
  • .
  • Additional active ingredients: hyaluronic acid and vitamin C
  • .
  • Form:sachets of powder to be dissolved in lukewarm water
  • .
  • Dosage: one sachet per day
  • .
  • Sufficient for: 30 days
  • .
See price
in the Natu.Care shop
Product description

Simple composition without unnecessary additivesós. High-quality fish collagen with vitamin C and hyaluronic acid. The active ingredients are designed to support the health and appearance of your skinóskin, hairóand nails.

Pros and cons

Simple composition without unnecessary additivesós. High-quality fish collagen with vitamin C and hyaluronic acid. The active ingredients are designed to support the health and appearance of your skinóskin, hairóand nails.

Additional information

Simple composition without unnecessary additivesós. High-quality fish collagen with vitamin C and hyaluronic acid. The active ingredients are designed to support the health and appearance of your skinóskin, hairóand nails.

User review

Simple composition without unnecessary additivesós. High-quality fish collagen with vitamin C and hyaluronic acid. The active ingredients are designed to support the health and appearance of your skinóskin, hairóand nails.

Aura Herbals Colladrop Glow

Aura Herbals Colladrop Glow
4.4
See price
in the Natu.Care shop
Product description

Fish collagen with hyaluronic acid and numerous – vitamins and minerals that support beauty and proper functioning of the body. The formula can positively influence the appearance of skinóry, hairów, nails, as well as jointsów.

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Pros and cons

Fish collagen with hyaluronic acid and numerous – vitamins and minerals that support beauty and proper functioning of the body. The formula can positively influence the appearance of skinóry, hairów, nails, as well as jointsów.

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Additional information

Fish collagen with hyaluronic acid and numerous – vitamins and minerals that support beauty and proper functioning of the body. The formula can positively influence the appearance of skinóry, hairów, nails, as well as jointsów.

.
User review

Fish collagen with hyaluronic acid and numerous – vitamins and minerals that support beauty and proper functioning of the body. The formula can positively influence the appearance of skinóry, hairów, nails, as well as jointsów.

.

ALLDEYNN Collarose Fish

ALLDEYNN Collarose Fish
4.7
  • Collagen content: 5000 mg hydrolysate fish collagen VERISOL F®
  • .
  • Additional active ingredients: vitamin Chyaluronic acidbiotin
  • Form: powder to dissolve in water
  • .
  • Dose: one scoop (6 g) of powder daily
  • .
  • Sufficient for: 50 days
  • .
See price
in the Natu.Care shop
Product description

Atlantic cod collagen VERISOL F® contained in the formula are easily absorbed collagen peptides of fish origin. Regular supplementation can firm your skinóhand and slow down the ageing process. Your nails will become stronger and stop breaking. The addition of biotin will improve the condition of your hairów. The collagen portion is high enough to also have a good effect on your joints, muscles and bones.

Pros and cons

Atlantic cod collagen VERISOL F® contained in the formula are easily absorbed collagen peptides of fish origin. Regular supplementation can firm your skinóhand and slow down the ageing process. Your nails will become stronger and stop breaking. The addition of biotin will improve the condition of your hairów. The collagen portion is high enough to also have a good effect on your joints, muscles and bones.

Additional information

Atlantic cod collagen VERISOL F® contained in the formula are easily absorbed collagen peptides of fish origin. Regular supplementation can firm your skinóhand and slow down the ageing process. Your nails will become stronger and stop breaking. The addition of biotin will improve the condition of your hairów. The collagen portion is high enough to also have a good effect on your joints, muscles and bones.

Expert and user opinion

Atlantic cod collagen VERISOL F® contained in the formula are easily absorbed collagen peptides of fish origin. Regular supplementation can firm your skinóhand and slow down the ageing process. Your nails will become stronger and stop breaking. The addition of biotin will improve the condition of your hairów. The collagen portion is high enough to also have a good effect on your joints, muscles and bones.

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Remember!

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Collagen supplementation is not a substitute for a balanced diet and healthy physical activity.

See also:

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Summary

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  • Lyophilised collagen is a form of collagen that has been stripped of water as a result of sublimation (freezing and evaporation).
  • It is long-lasting and stable, retaining its structure and original properties.
  • It is not a form of collagen.
  • There is no evidence that freeze-dried is superior to hydrolysed collagen.
  • .
  • In dietary supplements, hydrolysed collagen is commonly used - it is cheaper to obtain and better soluble in water.
  • After ingestion, both behave similarly in the body - they are broken down into amino acids from which your body 'builds collagen' anew.
  • .
  • When purchasing collagen products, greater importance should be given to the choice of collagen type, origin and form.
  • .
  • The most important selection criterion is the dose.
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  • Good supplements have at least 5000 mg of collagen per dose.
  • .
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FAQ

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. Does taking collagen make sense?.

Yes, taking collagen can make sense, especially for the elderly (we produce less and less of it every year), and for those who are noticing in themselves.

Supplements help replenish collagen deficiencies, and research confirms that, among other things, it improves skin elasticity, reduces joint pain and aids tissue regeneration.

Remember to consult your doctor before starting supplementation to select the right collagen and its dosage to avoid possible interactions with medications.

See what destroys collagen in the body and how to remedy it.

. What to look for when buying collagen?.

The key considerations when choosing collagen supplements are five: the purpose of the supplement (it will help determine which type of collagen you choose), the origin (fish, pork, poultry or maybe beef), form (natural, hydrolysate, freeze-dried, animal cartilage or collagen peptides), form (tablets, capsules, collagen powder and drink). The most important thing, however, is the dose - the higher the better. Research suggests it can go as high as 15,000 mg. Good collagen supplements typically have 5000-10000 mg.

See: What collagen to choose?

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. Is it safe to drink collagen?.

Drinking collagen is well tolerated. Occasionally, minor allergic reactions or indigestion may occur. If you want to avoid these, use tested preparations from trusted manufacturers and follow the recommended dosage.

Remember that collagen supplementation is not a substitute for a healthy diet and lifestyle, which are fundamental to maintaining good skin, hair and joint health.

See also, what the effects of drinking collagen are.

. With what is collagen best absorbed?.

If you want to increase the absorption of collagen, consume it together with foods rich in vitamin C (e.g. strawberries, citrus, kiwi, peppers, parsley). See these great recipes already? Also consider collagen supplements that have vitamin C in them, e.g. thanks to the presence of rosehip.

See also: When to drink collagen - morning or evening? An expert answers

. How long does a collagen treatment last?.

Visible improvements in the condition of skin, hair and nails, or a reduction in joint pain, are noticed by many people after about 2-3 months of regular supplementation. Research suggests that an optimal and safe dose is 2.5-15 g of collagen hydrolysate per day. You don't need to take any break. Remember that not everyone will get the same results at the same time.

See also: Collagen supplements - which one to choose?

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. Does collagen retain water in the body?.

Yes, collagen does retain water, but in a positive way. Water is crucial for collagen - it provides stability and influences collagen functionand. Adequate collagen means adequate hydration of the skin - making it smooth, firm and nourished. Collagen supplementation should not lead to water retention, which will negatively affect your health.

See also: Collagen for skin

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. What's better for joints - collagen or hyaluronic acid?.

Both collagen - especially type II - and hyaluronic acid can benefit your joint health. However, they work in slightly different ways.

Hyaluronic acid improves joint lubrication , and its injection helps treat knee osteoarthritis . In addition, it has an anti-inflammatory effect and relieves pain .

Type II collagen is a major component of connective tissue - including cartilage. Supplementation can aid cartilage regeneration, as well as reduce pain and improve joint flexibility.

There is still no direct research to conclusively determine which is better. It is suggestedand that the combination of both ingredients is beneficial - as they work synergistically and support joint health holistically.

See also: Collagen for joints

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Resources

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Akmal, M., Singh, A., Anand, A., Kesani, A., Aslam, N., Goodship, A., & Bentley, G. (2005). The effects of hyaluronic acid on articular chondrocytes. The Journal of Bone & Joint Surgery British Volume, 87-B(8), 1143-1149. https://doi.org/10.1302/0301-620X.87B8.15083

Avenue, 677 Huntington, Boston, & Ma 02115 (2021, May 26). Collagen. The Nutrition Source. https://www.hsph.harvard.edu/nutritionsource/collagen/

Beghé, F., Menicagli, C., Neggiani, P., Zampieri, A., Trallori, L., Teta, E., & Rosini, S. (1992). Lyophilized non-denatured type-I collagen (Condress) extracted from bovine Achilles' tendon and suitable for clinical use. International Journal of Tissue Reactions, 14 Suppl, 11-19. https://pubmed.ncbi.nlm.nih.gov/1639581/

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Di Mauro, C., Ossino, A. M., Trefiletti, M., Polosa, P., & Beghè, F. (1991). Lyophilized collagen in the treatment of diabetic ulcers. Drugs Under Experimental and Clinical Research, 17(7), 371-373. https://pubmed.ncbi.nlm.nih.gov/1794303/

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Lowe, C. J., Reucroft, I. M., Grotto, M. C., & Shreiber, D. I. (2016). Production of Highly Aligned Collagen Scaffolds by Freeze-drying of Self-assembled, Fibrillar Collagen Gels. ACS biomaterials science & engineering, 2(4), 643-651. https://doi.org/10.1021/acsbiomaterials.6b00036

Paul, C., Leser, S., & Oesser, S. (2019). Significant Amounts of Functional Collagen Peptides Can Be Incorporated in the Diet While Maintaining Indispensable Amino Acid Balance. Nutrients, 11(5), 1079. https://doi.org/10.3390/nu11051079

Radda, T. M., Menzel, E. J., Freyler, H., & Gnad, H. D. (1982). Collagen types in keratoconus. Graefe's Archive for Clinical and Experimental Ophthalmology, 218(5), 262-264. https://doi.org/10.1007/BF02175894

Ramachandran, G. n. (1988). Stereochemistry of collagen*. International Journal of Peptide and Protein Research, 31(1), 1-16. https://doi.org/10.1111/j.1399-3011.1988.tb00001.x

Ravikumar, K. M., & Hwang, W. (2008). Region-specific role of water in collagen unwinding and assembly. Proteins: Structure, Function, and Bioinformatics, 72(4), 1320-1332. https://doi.org/10.1002/prot.22026

Shepherd, J., Bax, D., Best, S., & Cameron, R. (2017). Collagen-Fibrinogen Lyophilised Scaffolds for Soft Tissue Regeneration. Materials, 10(6), 568. https://doi.org/10.3390/ma10060568

Shepherd, J. H., Ghose, S., Kew, S. J., Moavenian, A., Best, S. M., & Cameron, R. E. (2013). Effect of fiber crosslinking on collagen-fiber reinforced collagen-chondroitin-6-sulfate materials for regenerating load-bearing soft tissues. Journal of Biomedical Materials Research Part A, 101A(1), 176-184. https://doi.org/10.1002/jbm.a.34317

Skov, K., Oxfeldt, M., Thøgersen, R., Hansen, M., & Bertram, H. C. (2019). Enzymatic Hydrolysis of a Collagen Hydrolysate Enhances Postprandial Absorption Rate-A Randomized Controlled Trial. Nutrients, 11(5), 1064. https://doi.org/10.3390/nu11051064

Spitzner, E.-C., Röper, S., Zerson, M., Bernstein, A., & Magerle, R. (2015). Nanoscale Swelling Heterogeneities in Type I Collagen Fibrils. ACS Nano, 9(6), 5683-5694. https://doi.org/10.1021/nn503637q

Taroni, P., Comelli, D., Pifferi, A., Torricelli, A., & Cubeddu, R. (2007). Absorption of collagen: Effects on the estimate of breast composition and related diagnostic implications. Journal of Biomedical Optics, 12(1), 014021. https://doi.org/10.1117/1.2699170

Varley, M. C., Neelakantan, S., Clyne, T. W., Dean, J., Brooks, R. A., & Markaki, A. E. (2016). Cell structure, stiffness and permeability of freeze-dried collagen scaffolds in dry and hydrated states. Acta Biomaterialia, 33, 166-175. https://doi.org/10.1016/j.actbio.2016.01.041

Vilar, J. M., Rubio, M., Spinella, G., Cuervo, B., Sopena, J., Cugat, R., Garcia-Balletbó, M., Dominguez, J. M., Granados, M., Tvarijonaviciute, A., Ceron, J. J., & Carrillo, J. M. (2016). Serum Collagen Type II Cleavage Epitope and Serum Hyaluronic Acid as Biomarkers for Treatment Monitoring of Dogs with Hip Osteoarthritis. PLOS ONE, 11(2), e0149472. https://doi.org/10.1371/journal.pone.0149472

Yan, J., Li, X., Liu, L., Wang, F., Zhu, T. W., & Zhang, Q. (2006). Potential Use of Collagen-Chitosan-Hyaluronan Tri-Copolymer Scaffold for Cartilage Tissue Engineering. Artificial Cells, Blood Substitutes, and Biotechnology, 34(1), 27-39. https://doi.org/10.1080/10731190500430024

Yue, D. K., Swanson, B., McLennan, S., Marsh, M., Spaliviero, J., Delbridge, L., Reeve, T., & Turtle, J. R. (1986). Abnormalities of Granulation Tissue and Collagen Formation in Experimental Diabetes, Uraemia and Malnutrition. Diabetic Medicine, 3(3), 221-225. https://doi.org/10.1111/j.1464-5491.1986.tb00748.x

Jelonek, L. (2023). Collagen. Everything you need to know (B. Turczynski, ed.; 1st ed.). Natu.Care. https://books.google.com/books?vid=9788396887801

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